活動

2011年7月18日

下午五時至六時

香港中文大學行政樓地下祖堯堂

免費 (請於網上登記留座)

3943 8893

楊煥明教授簡歷

深圳華大基因研究院理事長

中國科學院院士

楊煥明教授，深圳華大基因研究院董事長，中國科學院院士，發展中國家科學院（TWAS）院士，印度科學院外籍院士，EMBO成員。

 「華大基因」為「人類基因組計劃」、「人類單體型圖計劃」等國際合作的基因組計劃，以及我國的水稻、家蠶等基因組的研究做出了重大貢獻。「深圳華大」是目前世界上最大的基因組研究中心。2009年以來，和合作者在《科學》和《自然》系列等雜誌上發表了「國際1000人基因組」、第一個亞洲人的基因組、人類古人類和pan-基因組、人類腸道meta-基因組以及黃瓜、大豆、玉米和大熊貓、螞蟻等基因組、外顯子組、轉錄組和甲基化組等「組學」的研究。

 「深圳華大」是「國際1000人基因組計劃」、「國際1000種植物基因組計劃」、「國際1000種動物基因組計劃」、「國際10000種微生物計劃」、「國際10000種脊椎動物基因組計劃」和 「世界三極動物基因組計劃」的主要倡議者和執行者。

講座摘要(English version only)

"Genomics and Personalized Medicine"

2011 sees the 10th anniversary of the first publication of the draft sequence of the human genome generated by the International Human Genome Project (HGP).  With the DNA sequence in hands as the reference, we further realize that we know so little about life and ourselves. 

The HGP has cultivated a new science, GENOMICS, and opened the door to Personalized Medicine which is characterized by and based on personal genome sequencing.  Genomics will bring more knowledge about human genome variations especially the population- or even individual-specific variations and those related to diseases, about evolution of our genomes especially the adaptation-related genes, about the microorganisms in our body especially host-microbe interactions, about the motablic/ signaling pathways and genome regulation network.

Sequencing technology will reshape the whole field of biomedicine.  The application of sequencing has been extended from Southern Sequencing (whole genome/ exome sequencing, trace/single cell sequencing, targeted sequencing, …), to Northern Sequencing (whole transcriptome sequencing, digital expression profiling, micro- and all other RNAseq), Western Sequencing (translatome/ regulatome sequencing, and other CHiP+seq), to Eastern Sequencing (methylome and other epigenome sequencing), and even more.